diff --git a/.betterer.results b/.betterer.results
index eedee48b81e..840c5291c87 100644
--- a/.betterer.results
+++ b/.betterer.results
@@ -11,9 +11,6 @@ exports[`no enzyme tests`] = {
     "packages/grafana-ui/src/components/ColorPicker/NamedColorsPalette.test.tsx:3311646309": [
       [0, 31, 13, "RegExp match", "2409514259"]
     ],
-    "packages/grafana-ui/src/components/FileUpload/FileUpload.test.tsx:4145620610": [
-      [0, 19, 13, "RegExp match", "2409514259"]
-    ],
     "packages/grafana-ui/src/components/FormField/FormField.test.tsx:3429087660": [
       [0, 19, 13, "RegExp match", "2409514259"]
     ],
diff --git a/packages/grafana-e2e-selectors/src/selectors/components.ts b/packages/grafana-e2e-selectors/src/selectors/components.ts
index 967ac2dc2a9..f226ae538d6 100644
--- a/packages/grafana-e2e-selectors/src/selectors/components.ts
+++ b/packages/grafana-e2e-selectors/src/selectors/components.ts
@@ -333,4 +333,8 @@ export const Components = {
     orgsTable: 'data-testid-user-orgs-table',
     sessionsTable: 'data-testid-user-sessions-table',
   },
+  FileUpload: {
+    inputField: 'data-testid-file-upload-input-field',
+    fileNameSpan: 'data-testid-file-upload-file-name',
+  },
 };
diff --git a/packages/grafana-ui/src/components/FileUpload/FileUpload.test.tsx b/packages/grafana-ui/src/components/FileUpload/FileUpload.test.tsx
index 8860c2efa62..01f1d9c0d78 100644
--- a/packages/grafana-ui/src/components/FileUpload/FileUpload.test.tsx
+++ b/packages/grafana-ui/src/components/FileUpload/FileUpload.test.tsx
@@ -1,33 +1,44 @@
-import { shallow } from 'enzyme';
+import { render, waitFor, fireEvent, screen } from '@testing-library/react';
 import React from 'react';
 
+import { selectors } from '@grafana/e2e-selectors';
+
 import { FileUpload } from './FileUpload';
 
 describe('FileUpload', () => {
   it('should render upload button with default text and no file name', () => {
-    const wrapper = shallow(<FileUpload onFileUpload={() => {}} />);
-    expect(wrapper.findWhere((comp) => comp.text() === 'Upload file').exists()).toBeTruthy();
-    expect(wrapper.find({ 'aria-label': 'File name' }).exists()).toBeFalsy();
+    render(<FileUpload onFileUpload={() => {}} />);
+    expect(screen.getByText('Upload file')).toBeInTheDocument();
+    expect(screen.queryByLabelText('File name')).toBeNull();
   });
 
-  it("should trim uploaded file's name", () => {
-    const wrapper = shallow(<FileUpload onFileUpload={() => {}} />);
+  it('should display uploaded file name', async () => {
+    const testFileName = 'grafana.png';
+    const file = new File(['(⌐□_□)'], testFileName, { type: 'image/png' });
+    const onFileUpload = jest.fn();
+    const { getByTestId } = render(<FileUpload onFileUpload={onFileUpload} />);
+    let uploader = getByTestId(selectors.components.FileUpload.inputField);
+    await waitFor(() =>
+      fireEvent.change(uploader, {
+        target: { files: [file] },
+      })
+    );
+    let uploaderLabel = getByTestId(selectors.components.FileUpload.fileNameSpan);
+    expect(uploaderLabel).toHaveTextContent(testFileName);
+  });
 
-    wrapper.find('input').simulate('change', {
-      currentTarget: {
-        files: [{ name: 'longFileName.something.png' }],
-      },
-    });
-    expect(wrapper.find({ 'aria-label': 'File name' }).exists()).toBeTruthy();
-    // Trim file name longer than 16 chars
-    expect(wrapper.find({ 'aria-label': 'File name' }).text()).toEqual('longFileName.som....png');
-
-    // Keep the name below the length limit intact
-    wrapper.find('input').simulate('change', {
-      currentTarget: {
-        files: [{ name: 'longFileName.png' }],
-      },
-    });
-    expect(wrapper.find({ 'aria-label': 'File name' }).text()).toEqual('longFileName.png');
+  it("should trim uploaded file's name", async () => {
+    const testFileName = 'longFileName.something.png';
+    const file = new File(['(⌐□_□)'], testFileName, { type: 'image/png' });
+    const onFileUpload = jest.fn();
+    const { getByTestId } = render(<FileUpload onFileUpload={onFileUpload} />);
+    let uploader = getByTestId(selectors.components.FileUpload.inputField);
+    await waitFor(() =>
+      fireEvent.change(uploader, {
+        target: { files: [file] },
+      })
+    );
+    let uploaderLabel = getByTestId(selectors.components.FileUpload.fileNameSpan);
+    expect(uploaderLabel).toHaveTextContent('longFileName.som....png');
   });
 });
diff --git a/packages/grafana-ui/src/components/FileUpload/FileUpload.tsx b/packages/grafana-ui/src/components/FileUpload/FileUpload.tsx
index 98fc47e7c5c..96a35fc5c00 100644
--- a/packages/grafana-ui/src/components/FileUpload/FileUpload.tsx
+++ b/packages/grafana-ui/src/components/FileUpload/FileUpload.tsx
@@ -2,8 +2,10 @@ import { css, cx } from '@emotion/css';
 import React, { FC, FormEvent, useCallback, useState } from 'react';
 
 import { GrafanaTheme2 } from '@grafana/data';
+import { selectors } from '@grafana/e2e-selectors';
 
-import { stylesFactory, useTheme2 } from '../../themes';
+import { useStyles2 } from '../../themes';
+import { getFocusStyles } from '../../themes/mixins';
 import { ComponentSize } from '../../types/size';
 import { trimFileName } from '../../utils/file';
 import { getButtonStyles } from '../Button';
@@ -27,8 +29,7 @@ export const FileUpload: FC<Props> = ({
   accept = '*',
   size = 'md',
 }) => {
-  const theme = useTheme2();
-  const style = getStyles(theme, size);
+  const style = useStyles2(getStyles(size));
   const [fileName, setFileName] = useState('');
 
   const onChange = useCallback(
@@ -44,20 +45,26 @@ export const FileUpload: FC<Props> = ({
 
   return (
     <>
-      <label className={cx(style.button, className)}>
+      <input
+        type="file"
+        id="fileUpload"
+        className={style.fileUpload}
+        onChange={onChange}
+        multiple={false}
+        accept={accept}
+        data-testid={selectors.components.FileUpload.inputField}
+      />
+      <label className={cx(style.labelWrapper, className)}>
         <Icon name="upload" className={style.icon} />
         {children}
-        <input
-          type="file"
-          id="fileUpload"
-          className={style.fileUpload}
-          onChange={onChange}
-          multiple={false}
-          accept={accept}
-        />
       </label>
+
       {fileName && (
-        <span aria-label="File name" className={style.fileName}>
+        <span
+          aria-label="File name"
+          className={style.fileName}
+          data-testid={selectors.components.FileUpload.fileNameSpan}
+        >
           {trimFileName(fileName)}
         </span>
       )}
@@ -65,16 +72,25 @@ export const FileUpload: FC<Props> = ({
   );
 };
 
-const getStyles = stylesFactory((theme: GrafanaTheme2, size: ComponentSize) => {
+const getStyles = (size: ComponentSize) => (theme: GrafanaTheme2) => {
   const buttonStyles = getButtonStyles({ theme, variant: 'primary', size, iconOnly: false });
+  const focusStyle = getFocusStyles(theme);
+
   return {
-    fileUpload: css`
-      display: none;
-    `,
-    button: buttonStyles.button,
+    fileUpload: css({
+      height: '0.1px',
+      opacity: '0',
+      overflow: 'hidden',
+      position: 'absolute',
+      width: '0.1px',
+      zIndex: -1,
+      '&:focus + label': focusStyle,
+      '&:focus-visible + label': focusStyle,
+    }),
+    labelWrapper: buttonStyles.button,
     icon: buttonStyles.icon,
-    fileName: css`
-      margin-left: ${theme.spacing(0.5)};
-    `,
+    fileName: css({
+      marginLeft: theme.spacing(0.5),
+    }),
   };
-});
+};