diff --git a/pkg/services/ngalert/remote/alertmanager.go b/pkg/services/ngalert/remote/alertmanager.go
index e57bd723696..87bfc8a1f6e 100644
--- a/pkg/services/ngalert/remote/alertmanager.go
+++ b/pkg/services/ngalert/remote/alertmanager.go
@@ -19,6 +19,7 @@ import (
 	"github.com/prometheus/client_golang/prometheus"
 
 	alertingClusterPB "github.com/grafana/alerting/cluster/clusterpb"
+	alertingModels "github.com/grafana/alerting/models"
 	alertingNotify "github.com/grafana/alerting/notify"
 
 	"gopkg.in/yaml.v3"
@@ -467,6 +468,16 @@ func (am *Alertmanager) GetAlertGroups(ctx context.Context, active, silenced, in
 }
 
 func (am *Alertmanager) PutAlerts(ctx context.Context, alerts apimodels.PostableAlerts) error {
+	for _, a := range alerts.PostableAlerts {
+		for k, v := range a.Labels {
+			// The Grafana Alertmanager skips empty and namespace UID labels.
+			// To get the same alert fingerprint we need to remove these labels too.
+			// https://github.com/grafana/alerting/blob/2dda1c67ec02625ac9fc8607157b3d5825d47919/notify/grafana_alertmanager.go#L722-L724
+			if len(v) == 0 || k == alertingModels.NamespaceUIDLabel {
+				delete(a.Labels, k)
+			}
+		}
+	}
 	am.log.Debug("Sending alerts to a remote alertmanager", "url", am.url, "alerts", len(alerts.PostableAlerts))
 	am.sender.SendAlerts(alerts)
 	return nil
diff --git a/pkg/services/ngalert/remote/alertmanager_test.go b/pkg/services/ngalert/remote/alertmanager_test.go
index ec3296badbc..b04c7194ee0 100644
--- a/pkg/services/ngalert/remote/alertmanager_test.go
+++ b/pkg/services/ngalert/remote/alertmanager_test.go
@@ -21,6 +21,7 @@ import (
 	"github.com/stretchr/testify/require"
 
 	"github.com/grafana/alerting/definition"
+	alertingModels "github.com/grafana/alerting/models"
 	"github.com/grafana/grafana/pkg/infra/db"
 	"github.com/grafana/grafana/pkg/infra/log"
 	"github.com/grafana/grafana/pkg/infra/tracing"
@@ -668,9 +669,9 @@ func TestIntegrationRemoteAlertmanagerAlerts(t *testing.T) {
 	require.Equal(t, 0, len(alertGroups))
 
 	// Let's create two active alerts and one expired one.
-	alert1 := genAlert(true, map[string]string{"test_1": "test_1"})
-	alert2 := genAlert(true, map[string]string{"test_2": "test_2"})
-	alert3 := genAlert(false, map[string]string{"test_3": "test_3"})
+	alert1 := genAlert(true, map[string]string{"test_1": "test_1", "empty": "", alertingModels.NamespaceUIDLabel: "test_1"})
+	alert2 := genAlert(true, map[string]string{"test_2": "test_2", "empty": "", alertingModels.NamespaceUIDLabel: "test_2"})
+	alert3 := genAlert(false, map[string]string{"test_3": "test_3", "empty": "", alertingModels.NamespaceUIDLabel: "test_3"})
 	postableAlerts := apimodels.PostableAlerts{
 		PostableAlerts: []amv2.PostableAlert{alert1, alert2, alert3},
 	}
@@ -688,6 +689,12 @@ func TestIntegrationRemoteAlertmanagerAlerts(t *testing.T) {
 	require.NoError(t, err)
 	require.Equal(t, 1, len(alertGroups))
 
+	// Labels with empty values and the namespace UID label should be removed.
+	for _, a := range alertGroups {
+		require.NotContains(t, a.Labels, "empty")
+		require.NotContains(t, a.Labels, alertingModels.NamespaceUIDLabel)
+	}
+
 	// Filtering by `test_1=test_1` should return one alert.
 	alerts, err = am.GetAlerts(context.Background(), true, true, true, []string{"test_1=test_1"}, "")
 	require.NoError(t, err)