diff --git a/packages/grafana-data/src/transformations/transformers/renameByRegex.test.ts b/packages/grafana-data/src/transformations/transformers/renameByRegex.test.ts
index aa630829a58..170811442db 100644
--- a/packages/grafana-data/src/transformations/transformers/renameByRegex.test.ts
+++ b/packages/grafana-data/src/transformations/transformers/renameByRegex.test.ts
@@ -80,6 +80,59 @@ describe('Rename By Regex Transformer', () => {
       });
     });
 
+    it('should be able to replace globally', async () => {
+      const cfg: DataTransformerConfig<RenameByRegexTransformerOptions> = {
+        id: DataTransformerID.renameByRegex,
+        options: {
+          regex: '/e/g',
+          renamePattern: 'E',
+        },
+      };
+      await expect(transformDataFrame([cfg], [data])).toEmitValuesWith((received) => {
+        const data = received[0];
+        const frame = data[0];
+        expect(frame.fields).toMatchInlineSnapshot(`
+          Array [
+            Object {
+              "config": Object {
+                "displayName": "TimE",
+                "name": "Time",
+              },
+              "name": "Time",
+              "state": Object {
+                "displayName": "TimE",
+                "multipleFrames": false,
+              },
+              "type": "time",
+              "values": Array [
+                3000,
+                4000,
+                5000,
+                6000,
+              ],
+            },
+            Object {
+              "config": Object {
+                "displayName": "wEb-01.ExamplE.com",
+              },
+              "name": "Value",
+              "state": Object {
+                "displayName": "wEb-01.ExamplE.com",
+                "multipleFrames": false,
+              },
+              "type": "number",
+              "values": Array [
+                10000.3,
+                10000.4,
+                10000.5,
+                10000.6,
+              ],
+            },
+          ]
+        `);
+      });
+    });
+
     it('should not rename misses', async () => {
       const cfg: DataTransformerConfig<RenameByRegexTransformerOptions> = {
         id: DataTransformerID.renameByRegex,
@@ -147,7 +200,6 @@ describe('Rename By Regex Transformer', () => {
           Array [
             Object {
               "config": Object {
-                "displayName": "Time",
                 "name": "Time",
               },
               "name": "Time",
diff --git a/packages/grafana-data/src/transformations/transformers/renameByRegex.ts b/packages/grafana-data/src/transformations/transformers/renameByRegex.ts
index 05426c988c0..ad6e2d39942 100644
--- a/packages/grafana-data/src/transformations/transformers/renameByRegex.ts
+++ b/packages/grafana-data/src/transformations/transformers/renameByRegex.ts
@@ -1,6 +1,7 @@
 import { map } from 'rxjs/operators';
 
 import { getFieldDisplayName } from '../../field/fieldState';
+import { stringToJsRegex } from '../../text/string';
 import { DataFrame } from '../../types/dataFrame';
 import { DataTransformerInfo } from '../../types/transformations';
 
@@ -47,7 +48,7 @@ export const renameByRegexTransformer: DataTransformerInfo<RenameByRegexTransfor
 };
 
 const renameFieldsByRegex = (options: RenameByRegexTransformerOptions) => (frame: DataFrame) => {
-  const regex = new RegExp(options.regex);
+  const regex = stringToJsRegex(options.regex);
   const fields = frame.fields.map((field) => {
     const displayName = getFieldDisplayName(field, frame);
     if (!regex.test(displayName)) {