diff --git a/.betterer.results b/.betterer.results
index 14165ffed3a..9648cb3d1e3 100644
--- a/.betterer.results
+++ b/.betterer.results
@@ -19,10 +19,6 @@ exports[`better eslint`] = {
       [0, 0, 0, "Do not use any type assertions.", "0"],
       [0, 0, 0, "Do not use any type assertions.", "1"]
     ],
-    "packages/grafana-data/src/dataframe/DataFrameView.test.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
-    ],
     "packages/grafana-data/src/dataframe/DataFrameView.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Do not use any type assertions.", "1"],
@@ -40,14 +36,12 @@ exports[`better eslint`] = {
       [0, 0, 0, "Unexpected any. Specify a different type.", "7"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "8"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "9"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "10"],
+      [0, 0, 0, "Do not use any type assertions.", "10"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "11"],
       [0, 0, 0, "Do not use any type assertions.", "12"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "13"],
-      [0, 0, 0, "Do not use any type assertions.", "14"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "15"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "16"],
-      [0, 0, 0, "Do not use any type assertions.", "17"]
+      [0, 0, 0, "Unexpected any. Specify a different type.", "14"],
+      [0, 0, 0, "Do not use any type assertions.", "15"]
     ],
     "packages/grafana-data/src/dataframe/StreamingDataFrame.ts:5381": [
       [0, 0, 0, "Do not use any type assertions.", "0"],
@@ -55,8 +49,7 @@ exports[`better eslint`] = {
       [0, 0, 0, "Do not use any type assertions.", "2"],
       [0, 0, 0, "Do not use any type assertions.", "3"],
       [0, 0, 0, "Do not use any type assertions.", "4"],
-      [0, 0, 0, "Do not use any type assertions.", "5"],
-      [0, 0, 0, "Do not use any type assertions.", "6"]
+      [0, 0, 0, "Do not use any type assertions.", "5"]
     ],
     "packages/grafana-data/src/dataframe/dimensions.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
@@ -129,10 +122,6 @@ exports[`better eslint`] = {
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
     ],
-    "packages/grafana-data/src/events/common.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
-    ],
     "packages/grafana-data/src/events/types.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
@@ -148,21 +137,13 @@ exports[`better eslint`] = {
     "packages/grafana-data/src/field/overrides/processors.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "2"],
-      [0, 0, 0, "Do not use any type assertions.", "3"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "4"],
-      [0, 0, 0, "Do not use any type assertions.", "5"],
+      [0, 0, 0, "Do not use any type assertions.", "2"],
+      [0, 0, 0, "Unexpected any. Specify a different type.", "3"],
+      [0, 0, 0, "Do not use any type assertions.", "4"],
+      [0, 0, 0, "Unexpected any. Specify a different type.", "5"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "6"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "7"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "8"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "9"],
-      [0, 0, 0, "Do not use any type assertions.", "10"]
-    ],
-    "packages/grafana-data/src/field/scale.ts:5381": [
-      [0, 0, 0, "Do not use any type assertions.", "0"],
-      [0, 0, 0, "Do not use any type assertions.", "1"],
-      [0, 0, 0, "Do not use any type assertions.", "2"],
-      [0, 0, 0, "Do not use any type assertions.", "3"]
+      [0, 0, 0, "Do not use any type assertions.", "8"]
     ],
     "packages/grafana-data/src/field/standardFieldConfigEditorRegistry.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
@@ -187,9 +168,6 @@ exports[`better eslint`] = {
       [0, 0, 0, "Do not use any type assertions.", "6"],
       [0, 0, 0, "Do not use any type assertions.", "7"]
     ],
-    "packages/grafana-data/src/panel/getPanelOptionsWithDefaults.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
-    ],
     "packages/grafana-data/src/panel/registryFactories.ts:5381": [
       [0, 0, 0, "Do not use any type assertions.", "0"]
     ],
@@ -211,37 +189,15 @@ exports[`better eslint`] = {
     "packages/grafana-data/src/transformations/transformDataFrame.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
     ],
-    "packages/grafana-data/src/transformations/transformers/groupBy.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
-    ],
-    "packages/grafana-data/src/transformations/transformers/groupingToMatrix.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
-    ],
-    "packages/grafana-data/src/transformations/transformers/histogram.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
-    ],
     "packages/grafana-data/src/transformations/transformers/joinDataFrames.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
     ],
-    "packages/grafana-data/src/transformations/transformers/merge.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "2"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "3"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "4"]
-    ],
     "packages/grafana-data/src/transformations/transformers/nulls/nullInsertThreshold.ts:5381": [
       [0, 0, 0, "Do not use any type assertions.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "2"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "3"]
     ],
-    "packages/grafana-data/src/transformations/transformers/nulls/nullToUndefThreshold.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Do not use any type assertions.", "2"]
-    ],
     "packages/grafana-data/src/transformations/transformers/reduce.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
@@ -398,8 +354,7 @@ exports[`better eslint`] = {
     ],
     "packages/grafana-data/src/types/plugin.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Do not use any type assertions.", "2"]
+      [0, 0, 0, "Do not use any type assertions.", "1"]
     ],
     "packages/grafana-data/src/types/select.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
@@ -540,34 +495,26 @@ exports[`better eslint`] = {
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
     ],
     "packages/grafana-data/src/utils/datasource.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "2"],
-      [0, 0, 0, "Do not use any type assertions.", "3"],
-      [0, 0, 0, "Do not use any type assertions.", "4"]
-    ],
-    "packages/grafana-data/src/utils/fieldParser.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
+      [0, 0, 0, "Do not use any type assertions.", "0"],
+      [0, 0, 0, "Do not use any type assertions.", "1"]
     ],
     "packages/grafana-data/src/utils/flotPairs.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
     ],
     "packages/grafana-data/src/utils/location.ts:5381": [
       [0, 0, 0, "Do not use any type assertions.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "2"]
+      [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
     ],
     "packages/grafana-data/src/utils/url.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "1"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "2"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "3"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "4"],
-      [0, 0, 0, "Do not use any type assertions.", "5"],
+      [0, 0, 0, "Do not use any type assertions.", "4"],
+      [0, 0, 0, "Unexpected any. Specify a different type.", "5"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "6"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "7"],
-      [0, 0, 0, "Do not use any type assertions.", "8"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "9"]
+      [0, 0, 0, "Do not use any type assertions.", "7"],
+      [0, 0, 0, "Unexpected any. Specify a different type.", "8"]
     ],
     "packages/grafana-data/src/utils/valueMappings.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
@@ -587,8 +534,7 @@ exports[`better eslint`] = {
       [0, 0, 0, "Unexpected any. Specify a different type.", "2"]
     ],
     "packages/grafana-data/src/vector/CircularVector.ts:5381": [
-      [0, 0, 0, "Unexpected any. Specify a different type.", "0"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "1"]
+      [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
     ],
     "packages/grafana-data/src/vector/ConstantVector.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
@@ -606,8 +552,7 @@ exports[`better eslint`] = {
       [0, 0, 0, "Unexpected any. Specify a different type.", "6"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "7"],
       [0, 0, 0, "Unexpected any. Specify a different type.", "8"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "9"],
-      [0, 0, 0, "Unexpected any. Specify a different type.", "10"]
+      [0, 0, 0, "Unexpected any. Specify a different type.", "9"]
     ],
     "packages/grafana-data/src/vector/SortedVector.ts:5381": [
       [0, 0, 0, "Unexpected any. Specify a different type.", "0"]
diff --git a/packages/grafana-data/src/dataframe/DataFrameView.test.ts b/packages/grafana-data/src/dataframe/DataFrameView.test.ts
index 8975da7b24f..dca646c3ec0 100644
--- a/packages/grafana-data/src/dataframe/DataFrameView.test.ts
+++ b/packages/grafana-data/src/dataframe/DataFrameView.test.ts
@@ -46,7 +46,12 @@ describe('dataFrameView', () => {
   it('Should support array indexes', () => {
     expect(vector.length).toEqual(3);
 
-    const first = vector.get(0) as any;
+    const first = vector.get(0) as unknown as [
+      MySpecialObject['time'],
+      MySpecialObject['name'],
+      MySpecialObject['value'],
+      MySpecialObject['more'],
+    ];
     expect(first[0]).toEqual(100);
     expect(first[1]).toEqual('a');
     expect(first[2]).toEqual(1);
@@ -84,7 +89,10 @@ describe('dataFrameView', () => {
   });
 
   it('Can handle fields with number name', () => {
-    const view = new DataFrameView<MySpecialObject>(
+    const view = new DataFrameView<{
+      '1': string;
+      '2': string;
+    }>(
       new MutableDataFrame({
         fields: [
           { name: '1', type: FieldType.string, values: ['a'] },
@@ -93,7 +101,7 @@ describe('dataFrameView', () => {
       })
     );
 
-    const obj = view.get(0) as any;
+    const obj = view.get(0);
     expect(obj['1']).toEqual('a');
     expect(obj['2']).toEqual('b');
   });
diff --git a/packages/grafana-data/src/dataframe/MutableDataFrame.ts b/packages/grafana-data/src/dataframe/MutableDataFrame.ts
index 7d96a8f592c..84a02a33679 100644
--- a/packages/grafana-data/src/dataframe/MutableDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/MutableDataFrame.ts
@@ -162,7 +162,7 @@ export class MutableDataFrame<T = any> extends FunctionalVector<T> implements Da
     return parser;
   }
 
-  private parseValue(field: Field, v: any): any {
+  private parseValue(field: Field, v: string) {
     let p = this.parsers?.get(field);
     if (!p) {
       p = this.setParser(field, makeFieldParser(v, field));
diff --git a/packages/grafana-data/src/dataframe/StreamingDataFrame.ts b/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
index d0de4ef1eeb..36fe7a77e22 100644
--- a/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
@@ -123,7 +123,7 @@ export class StreamingDataFrame implements DataFrame {
 
     dataFrameDTO.fields = dataFrameDTO.fields.map((f) => ({
       ...f,
-      values: (f.values as unknown[]).slice(numberOfItemsToRemove),
+      values: f.values?.slice(numberOfItemsToRemove),
     }));
 
     const length = dataFrameDTO.fields[0]?.values?.length ?? 0;
diff --git a/packages/grafana-data/src/events/common.ts b/packages/grafana-data/src/events/common.ts
index 588b6a6d30d..6b480a834f3 100644
--- a/packages/grafana-data/src/events/common.ts
+++ b/packages/grafana-data/src/events/common.ts
@@ -17,8 +17,8 @@ export interface DataHoverPayload {
   dataId?: string; // identifying string to correlate data between publishers and subscribers
 
   // When dragging, this will capture the point when the mouse was down
-  point: Record<string, any>; // { time: 5678, lengthft: 456 }  // each axis|scale gets a value
-  down?: Record<string, any>;
+  point: Record<string, number | null>; // { time: 5678, lengthft: 456 }  // each axis|scale gets a value
+  down?: Record<string, number | null>;
 }
 
 /** @alpha */
diff --git a/packages/grafana-data/src/field/overrides/processors.ts b/packages/grafana-data/src/field/overrides/processors.ts
index 409b0bdab68..5394c692cd5 100644
--- a/packages/grafana-data/src/field/overrides/processors.ts
+++ b/packages/grafana-data/src/field/overrides/processors.ts
@@ -33,7 +33,7 @@ export const numberOverrideProcessor = (
 };
 
 export const displayNameOverrideProcessor = (
-  value: any,
+  value: unknown,
   context: FieldOverrideContext,
   settings?: StringFieldConfigSettings
 ) => {
@@ -100,14 +100,14 @@ export interface StringFieldConfigSettings {
 }
 
 export const stringOverrideProcessor = (
-  value: any,
+  value: unknown,
   context: FieldOverrideContext,
   settings?: StringFieldConfigSettings
 ) => {
   if (value === null || value === undefined) {
     return value;
   }
-  if (settings && settings.expandTemplateVars && context.replaceVariables) {
+  if (settings && settings.expandTemplateVars && context.replaceVariables && typeof value === 'string') {
     return context.replaceVariables(value, context.field!.state!.scopedVars);
   }
   return `${value}`;
diff --git a/packages/grafana-data/src/field/scale.ts b/packages/grafana-data/src/field/scale.ts
index e97b01faf94..c8624e6086f 100644
--- a/packages/grafana-data/src/field/scale.ts
+++ b/packages/grafana-data/src/field/scale.ts
@@ -9,7 +9,7 @@ import { getActiveThresholdForValue } from './thresholds';
 
 export interface ColorScaleValue {
   percent: number; // 0-1
-  threshold: Threshold;
+  threshold: Threshold | undefined;
   color: string;
 }
 
@@ -49,13 +49,13 @@ function getBooleanScaleCalculator(field: Field, theme: GrafanaTheme2): ScaleCal
   const trueValue: ColorScaleValue = {
     color: theme.visualization.getColorByName('green'),
     percent: 1,
-    threshold: undefined as unknown as Threshold,
+    threshold: undefined,
   };
 
   const falseValue: ColorScaleValue = {
     color: theme.visualization.getColorByName('red'),
     percent: 0,
-    threshold: undefined as unknown as Threshold,
+    threshold: undefined,
   };
 
   const mode = getFieldColorModeForField(field);
diff --git a/packages/grafana-data/src/panel/getPanelOptionsWithDefaults.ts b/packages/grafana-data/src/panel/getPanelOptionsWithDefaults.ts
index 584ea189989..f3a8d44faf7 100644
--- a/packages/grafana-data/src/panel/getPanelOptionsWithDefaults.ts
+++ b/packages/grafana-data/src/panel/getPanelOptionsWithDefaults.ts
@@ -111,11 +111,10 @@ export function filterFieldConfigOverrides(
     .filter((x) => x.properties.length > 0);
 }
 
-function cleanProperties(obj: any, parentPath: string, fieldConfigRegistry: FieldConfigOptionsRegistry) {
+function cleanProperties(obj: object, parentPath: string, fieldConfigRegistry: FieldConfigOptionsRegistry) {
   let found = false;
 
-  for (const propName of Object.keys(obj)) {
-    const value = obj[propName];
+  for (const [propName, value] of Object.entries(obj)) {
     const fullPath = `${parentPath}${propName}`;
     const existsInRegistry = !!fieldConfigRegistry.getIfExists(fullPath);
 
diff --git a/packages/grafana-data/src/transformations/transformers/groupBy.ts b/packages/grafana-data/src/transformations/transformers/groupBy.ts
index e57d15ed9b3..3fd95db316b 100644
--- a/packages/grafana-data/src/transformations/transformers/groupBy.ts
+++ b/packages/grafana-data/src/transformations/transformers/groupBy.ts
@@ -117,7 +117,7 @@ export const groupByTransformer: DataTransformerInfo<GroupByTransformerOptions>
           const fields: Field[] = [];
 
           for (const field of groupByFields) {
-            const values: any[] = [];
+            const values: unknown[] = [];
             const fieldName = getFieldDisplayName(field);
 
             valuesByGroupKey.forEach((value) => {
@@ -142,7 +142,7 @@ export const groupByTransformer: DataTransformerInfo<GroupByTransformerOptions>
 
             const fieldName = getFieldDisplayName(field);
             const aggregations = options.fields[fieldName].aggregations;
-            const valuesByAggregation: Record<string, any[]> = {};
+            const valuesByAggregation: Record<string, unknown[]> = {};
 
             valuesByGroupKey.forEach((value) => {
               const fieldWithValuesForGroup = value[fieldName];
diff --git a/packages/grafana-data/src/transformations/transformers/groupingToMatrix.ts b/packages/grafana-data/src/transformations/transformers/groupingToMatrix.ts
index f600b5ee7ba..bb1dcd445d4 100644
--- a/packages/grafana-data/src/transformations/transformers/groupingToMatrix.ts
+++ b/packages/grafana-data/src/transformations/transformers/groupingToMatrix.ts
@@ -89,7 +89,7 @@ export const groupingToMatrixTransformer: DataTransformerInfo<GroupingToMatrixTr
         const columnValues = uniqueValues(keyColumnField.values);
         const rowValues = uniqueValues(keyRowField.values);
 
-        const matrixValues: { [key: string]: { [key: string]: any } } = {};
+        const matrixValues: { [key: string]: { [key: string]: unknown } } = {};
 
         for (let index = 0; index < valueField.values.length; index++) {
           const columnName = keyColumnField.values[index];
diff --git a/packages/grafana-data/src/transformations/transformers/histogram.ts b/packages/grafana-data/src/transformations/transformers/histogram.ts
index 1a8f8d858e7..7edf737f62d 100644
--- a/packages/grafana-data/src/transformations/transformers/histogram.ts
+++ b/packages/grafana-data/src/transformations/transformers/histogram.ts
@@ -38,7 +38,7 @@ export const histogramBucketSizes = [
 ];
 /* eslint-enable */
 
-const histFilter = [null];
+const histFilter: number[] = [];
 const histSort = (a: number, b: number) => a - b;
 
 export interface HistogramTransformerInputs {
@@ -496,7 +496,7 @@ export function incrRoundDn(num: number, incr: number) {
 function histogram(
   vals: number[],
   getBucket: (v: number) => number,
-  filterOut?: any[] | null,
+  filterOut?: number[],
   sort?: ((a: number, b: number) => number) | null
 ): AlignedData {
   let hist = new Map();
diff --git a/packages/grafana-data/src/transformations/transformers/merge.ts b/packages/grafana-data/src/transformations/transformers/merge.ts
index 5abf270b6e5..4c783acf42c 100644
--- a/packages/grafana-data/src/transformations/transformers/merge.ts
+++ b/packages/grafana-data/src/transformations/transformers/merge.ts
@@ -73,7 +73,7 @@ export const mergeTransformer: DataTransformerInfo<MergeTransformerOptions> = {
           return dataFrames;
         }
 
-        const valuesByKey: Record<string, Array<Record<string, any>>> = {};
+        const valuesByKey: Record<string, Array<Record<string, unknown>>> = {};
         const valuesInOrder: ValuePointer[] = [];
         const keyFactory = createKeyFactory(data, fieldIndexByName, fieldNamesForKey);
         const valueMapper = createValueMapper(data, fieldNames, fieldIndexByName);
@@ -157,7 +157,7 @@ const createValueMapper = (
   fieldIndexByName: Record<string, Record<number, number>>
 ) => {
   return (frameIndex: number, valueIndex: number) => {
-    const value: Record<string, any> = {};
+    const value: Record<string, unknown> = {};
     const fieldNames = Array.from(fieldByName);
 
     for (const fieldName of fieldNames) {
@@ -188,7 +188,7 @@ const createValueMapper = (
   };
 };
 
-const isMergable = (existing: Record<string, any>, value: Record<string, any>): boolean => {
+const isMergable = (existing: Record<string, unknown>, value: Record<string, unknown>): boolean => {
   let mergable = true;
 
   for (const prop in value) {
@@ -217,7 +217,7 @@ const fieldExistsInAllFrames = (
   return Object.keys(fieldIndexByName[field.name]).length === data.length;
 };
 
-const createPointer = (key: string, valuesByKey: Record<string, Array<Record<string, any>>>): ValuePointer => {
+const createPointer = (key: string, valuesByKey: Record<string, Array<Record<string, unknown>>>): ValuePointer => {
   return {
     key,
     index: valuesByKey[key].length - 1,
diff --git a/packages/grafana-data/src/transformations/transformers/nulls/nullToUndefThreshold.ts b/packages/grafana-data/src/transformations/transformers/nulls/nullToUndefThreshold.ts
index dacc82a63fa..7003ede81ab 100644
--- a/packages/grafana-data/src/transformations/transformers/nulls/nullToUndefThreshold.ts
+++ b/packages/grafana-data/src/transformations/transformers/nulls/nullToUndefThreshold.ts
@@ -1,6 +1,6 @@
 // mutates all nulls -> undefineds in the fieldValues array for value-less refValues ranges below maxThreshold
 // refValues is typically a time array and maxThreshold is the allowable distance between in time
-export function nullToUndefThreshold(refValues: number[], fieldValues: any[], maxThreshold: number): any[] {
+export function nullToUndefThreshold(refValues: number[], fieldValues: unknown[], maxThreshold: number) {
   let prevRef;
   let nullIdx;
 
@@ -12,8 +12,8 @@ export function nullToUndefThreshold(refValues: number[], fieldValues: any[], ma
         nullIdx = i;
       }
     } else {
-      if (nullIdx != null) {
-        if (refValues[i] - (prevRef as number) < maxThreshold) {
+      if (nullIdx != null && prevRef != null) {
+        if (refValues[i] - prevRef < maxThreshold) {
           while (nullIdx < i) {
             fieldValues[nullIdx++] = undefined;
           }
diff --git a/packages/grafana-data/src/types/plugin.ts b/packages/grafana-data/src/types/plugin.ts
index b67f1294655..7d07e91f018 100644
--- a/packages/grafana-data/src/types/plugin.ts
+++ b/packages/grafana-data/src/types/plugin.ts
@@ -203,7 +203,7 @@ export class GrafanaPlugin<T extends PluginMeta = PluginMeta> {
   /**
    * @deprecated -- this is no longer necessary and will be removed
    */
-  setChannelSupport(support: any) {
+  setChannelSupport() {
     console.warn('[deprecation] plugin is using ignored option: setChannelSupport', this.meta);
     return this;
   }
diff --git a/packages/grafana-data/src/utils/datasource.ts b/packages/grafana-data/src/utils/datasource.ts
index 42f8811cce9..19d7971986a 100644
--- a/packages/grafana-data/src/utils/datasource.ts
+++ b/packages/grafana-data/src/utils/datasource.ts
@@ -94,7 +94,7 @@ export const onUpdateDatasourceResetOption =
 export function updateDatasourcePluginOption<J extends DataSourceJsonData, S extends {} = KeyValue>(
   props: DataSourcePluginOptionsEditorProps<J, S>,
   key: keyof DataSourceSettings,
-  val: any
+  val: unknown
 ) {
   const config = props.options;
 
@@ -107,7 +107,7 @@ export function updateDatasourcePluginOption<J extends DataSourceJsonData, S ext
 export const updateDatasourcePluginJsonDataOption = <J extends DataSourceJsonData, S, K extends keyof J>(
   props: DataSourcePluginOptionsEditorProps<J, S>,
   key: K,
-  val: any
+  val: unknown
 ) => {
   const config = props.options;
 
@@ -123,7 +123,7 @@ export const updateDatasourcePluginJsonDataOption = <J extends DataSourceJsonDat
 export const updateDatasourcePluginSecureJsonDataOption = <J extends DataSourceJsonData, S extends {} = KeyValue>(
   props: DataSourcePluginOptionsEditorProps<J, S>,
   key: string,
-  val: any
+  val: unknown
 ) => {
   const config = props.options;
 
diff --git a/packages/grafana-data/src/utils/fieldParser.ts b/packages/grafana-data/src/utils/fieldParser.ts
index fd1b07ec519..c6ab0183be1 100644
--- a/packages/grafana-data/src/utils/fieldParser.ts
+++ b/packages/grafana-data/src/utils/fieldParser.ts
@@ -1,7 +1,7 @@
 import { guessFieldTypeFromValue } from '../dataframe/processDataFrame';
 import { Field, FieldType } from '../types/dataFrame';
 
-export function makeFieldParser(value: unknown, field: Field): (value: string) => any {
+export function makeFieldParser(value: unknown, field: Field) {
   if (!field.type) {
     if (field.name === 'time' || field.name === 'Time') {
       field.type = FieldType.time;
diff --git a/packages/grafana-data/src/utils/location.ts b/packages/grafana-data/src/utils/location.ts
index 7897e860c52..44d42f247a5 100644
--- a/packages/grafana-data/src/utils/location.ts
+++ b/packages/grafana-data/src/utils/location.ts
@@ -69,7 +69,7 @@ const assureBaseUrl = (url: string): string => {
  * @param searchParamsToUpdate
  * @returns
  */
-const getUrlForPartial = (location: Location<any>, searchParamsToUpdate: Record<string, any>) => {
+const getUrlForPartial = (location: Location<any>, searchParamsToUpdate: UrlQueryMap) => {
   const searchParams = urlUtil.parseKeyValue(
     location.search.startsWith('?') ? location.search.substring(1) : location.search
   );
diff --git a/packages/grafana-data/src/utils/url.ts b/packages/grafana-data/src/utils/url.ts
index e3a602e0059..2ee35d9f449 100644
--- a/packages/grafana-data/src/utils/url.ts
+++ b/packages/grafana-data/src/utils/url.ts
@@ -54,7 +54,7 @@ function toUrlParams(a: any, encodeAsAngularJS = true) {
         encodeURIComponentAsAngularJS(value, pctEncodeSpaces)
     : (value: EncodeURIComponentParams, _: boolean) => encodeURIComponent(value);
 
-  const isArray = (obj: any) => {
+  const isArray = (obj: unknown) => {
     return Object.prototype.toString.call(obj) === '[object Array]';
   };
 
diff --git a/packages/grafana-data/src/vector/CircularVector.ts b/packages/grafana-data/src/vector/CircularVector.ts
index aa70ae27578..fa3bd2503a8 100644
--- a/packages/grafana-data/src/vector/CircularVector.ts
+++ b/packages/grafana-data/src/vector/CircularVector.ts
@@ -122,7 +122,7 @@ export class CircularVector<T = any> extends FunctionalVector<T> {
     return this.buffer[(index + this.index) % this.buffer.length];
   }
 
-  set(index: number, value: any) {
+  set(index: number, value: T) {
     this.buffer[(index + this.index) % this.buffer.length] = value;
   }
 
diff --git a/packages/grafana-data/src/vector/FunctionalVector.ts b/packages/grafana-data/src/vector/FunctionalVector.ts
index fa6a0420a67..5c2984c4b72 100644
--- a/packages/grafana-data/src/vector/FunctionalVector.ts
+++ b/packages/grafana-data/src/vector/FunctionalVector.ts
@@ -18,7 +18,7 @@ export abstract class FunctionalVector<T = any> implements Vector<T> {
     }
   }
 
-  set(index: number, value: any): void {
+  set(index: number, value: T): void {
     throw 'unsupported operation';
   }
 
diff --git a/public/app/plugins/panel/geomap/layers/data/dayNightLayer.tsx b/public/app/plugins/panel/geomap/layers/data/dayNightLayer.tsx
index fe50748812d..e9ef19af26f 100644
--- a/public/app/plugins/panel/geomap/layers/data/dayNightLayer.tsx
+++ b/public/app/plugins/panel/geomap/layers/data/dayNightLayer.tsx
@@ -163,7 +163,7 @@ export const dayNightLayer: MapLayerRegistryItem<DayNightConfig> = {
     if (false) {
       subscriptions.add(
         eventBus.subscribe(DataHoverEvent, (event) => {
-          const time: number = event.payload?.point?.time;
+          const time = event.payload?.point?.time;
           if (time) {
             const lineTime = new Date(time);
             const nightLinePoints = sourceLine.getCoordinates(lineTime.toString(), 'line');
diff --git a/public/app/plugins/panel/geomap/layers/data/routeLayer.tsx b/public/app/plugins/panel/geomap/layers/data/routeLayer.tsx
index 286c07c4fbe..d7f86b10ab0 100644
--- a/public/app/plugins/panel/geomap/layers/data/routeLayer.tsx
+++ b/public/app/plugins/panel/geomap/layers/data/routeLayer.tsx
@@ -252,7 +252,7 @@ export const routeLayer: MapLayerRegistryItem<RouteConfig> = {
             const mapExtents = map.getView().calculateExtent(map.getSize());
             const feature = source.getFeatures()[0];
             const frame: DataFrame = feature?.get('frame');
-            const time: number = event.payload?.point?.time;
+            const time = event.payload?.point?.time;
             if (frame && time) {
               const timeField = frame.fields.find((f) => f.type === FieldType.time);
               if (timeField) {