diff --git a/e2e/various-suite/verify-i18n.spec.ts b/e2e/various-suite/verify-i18n.spec.ts
new file mode 100644
index 00000000000..3de37d5d863
--- /dev/null
+++ b/e2e/various-suite/verify-i18n.spec.ts
@@ -0,0 +1,65 @@
+import { e2e } from '../utils';
+import { fromBaseUrl } from '../utils/support/url';
+
+describe('Verify i18n', () => {
+  const I18N_USER = 'i18n-test';
+  const I18N_PASSWORD = 'i18n-test';
+
+  // create a new user to isolate the language changes from other tests
+  before(() => {
+    e2e.flows.login(Cypress.env('USERNAME'), Cypress.env('PASSWORD'));
+    cy.request({
+      method: 'POST',
+      url: fromBaseUrl('/api/admin/users'),
+      body: {
+        email: I18N_USER,
+        login: I18N_USER,
+        name: I18N_USER,
+        password: I18N_PASSWORD,
+      },
+    }).then((response) => {
+      cy.wrap(response.body.uid).as('uid');
+    });
+  });
+
+  // remove the user created in the before hook
+  after(() => {
+    e2e.flows.login(Cypress.env('USERNAME'), Cypress.env('PASSWORD'));
+    cy.get('@uid').then((uid) => {
+      cy.request({
+        method: 'DELETE',
+        url: fromBaseUrl(`/api/admin/users/${uid}`),
+      });
+    });
+  });
+
+  beforeEach(() => {
+    e2e.flows.login(I18N_USER, I18N_PASSWORD);
+  });
+
+  // map between languages in the language picker and the corresponding translation of the 'Language' label
+  const languageMap: Record<string, string> = {
+    Deutsch: 'Sprache',
+    English: 'Language',
+    Español: 'Idioma',
+    Français: 'Langue',
+    'Português Brasileiro': 'Idioma',
+    '中文（简体）': '语言',
+  };
+
+  // basic test which loops through the defined languages in the picker
+  // and verifies that the corresponding label is translated correctly
+  it('loads all the languages correctly', () => {
+    cy.visit('/profile');
+    const LANGUAGE_SELECTOR = '[id="locale-select"]';
+
+    cy.wrap(Object.entries(languageMap)).each(([language, label]: [string, string]) => {
+      cy.get(LANGUAGE_SELECTOR).should('not.be.disabled');
+      cy.get(LANGUAGE_SELECTOR).click();
+      cy.get(LANGUAGE_SELECTOR).clear().type(language).type('{downArrow}{enter}');
+      e2e.components.UserProfile.preferencesSaveButton().click();
+      cy.contains('label', label).should('be.visible');
+      cy.get(LANGUAGE_SELECTOR).should('have.value', language);
+    });
+  });
+});
diff --git a/public/app/core/components/SharedPreferences/SharedPreferences.tsx b/public/app/core/components/SharedPreferences/SharedPreferences.tsx
index cd6475c45ac..462e38863a5 100644
--- a/public/app/core/components/SharedPreferences/SharedPreferences.tsx
+++ b/public/app/core/components/SharedPreferences/SharedPreferences.tsx
@@ -31,7 +31,9 @@ export interface Props {
   onConfirm?: () => Promise<boolean>;
 }
 
-export type State = UserPreferencesDTO;
+export type State = UserPreferencesDTO & {
+  isLoading: boolean;
+};
 
 function getLanguageOptions(): ComboboxOption[] {
   const languageOptions = LANGUAGES.map((v) => ({
@@ -69,6 +71,7 @@ export class SharedPreferences extends PureComponent<Props, State> {
 
     this.service = new PreferencesService(props.resourceUri);
     this.state = {
+      isLoading: false,
       theme: '',
       timezone: '',
       weekStart: '',
@@ -87,9 +90,13 @@ export class SharedPreferences extends PureComponent<Props, State> {
   }
 
   async componentDidMount() {
+    this.setState({
+      isLoading: true,
+    });
     const prefs = await this.service.load();
 
     this.setState({
+      isLoading: false,
       homeDashboardUID: prefs.homeDashboardUID,
       theme: prefs.theme,
       timezone: prefs.timezone,
@@ -144,7 +151,7 @@ export class SharedPreferences extends PureComponent<Props, State> {
   };
 
   render() {
-    const { theme, timezone, weekStart, homeDashboardUID, language } = this.state;
+    const { theme, timezone, weekStart, homeDashboardUID, language, isLoading } = this.state;
     const { disabled } = this.props;
     const styles = getStyles();
     const languages = getLanguageOptions();
@@ -153,7 +160,11 @@ export class SharedPreferences extends PureComponent<Props, State> {
     return (
       <form onSubmit={this.onSubmitForm} className={styles.form}>
         <FieldSet label={<Trans i18nKey="shared-preferences.title">Preferences</Trans>} disabled={disabled}>
-          <Field label={t('shared-preferences.fields.theme-label', 'Interface theme')}>
+          <Field
+            loading={isLoading}
+            disabled={isLoading}
+            label={t('shared-preferences.fields.theme-label', 'Interface theme')}
+          >
             <Combobox
               options={this.themeOptions}
               value={currentThemeOption.value}
@@ -163,6 +174,8 @@ export class SharedPreferences extends PureComponent<Props, State> {
           </Field>
 
           <Field
+            loading={isLoading}
+            disabled={isLoading}
             label={
               <Label htmlFor="home-dashboard-select">
                 <span className={styles.labelText}>
@@ -183,6 +196,8 @@ export class SharedPreferences extends PureComponent<Props, State> {
           </Field>
 
           <Field
+            loading={isLoading}
+            disabled={isLoading}
             label={t('shared-dashboard.fields.timezone-label', 'Timezone')}
             data-testid={selectors.components.TimeZonePicker.containerV2}
           >
@@ -195,17 +210,21 @@ export class SharedPreferences extends PureComponent<Props, State> {
           </Field>
 
           <Field
+            loading={isLoading}
+            disabled={isLoading}
             label={t('shared-preferences.fields.week-start-label', 'Week start')}
             data-testid={selectors.components.WeekStartPicker.containerV2}
           >
             <WeekStartPicker
               value={weekStart || ''}
               onChange={this.onWeekStartChanged}
-              inputId={'shared-preferences-week-start-picker'}
+              inputId="shared-preferences-week-start-picker"
             />
           </Field>
 
           <Field
+            loading={isLoading}
+            disabled={isLoading}
             label={
               <Label htmlFor="locale-select">
                 <span className={styles.labelText}>
diff --git a/public/app/core/internationalization/constants.test.ts b/public/app/core/internationalization/constants.test.ts
index 6dee3878b36..68defb081b3 100644
--- a/public/app/core/internationalization/constants.test.ts
+++ b/public/app/core/internationalization/constants.test.ts
@@ -21,7 +21,7 @@ describe('internationalization constants', () => {
     expect(GERMAN_GERMANY).toBe('de-DE');
     expect(BRAZILIAN_PORTUGUESE).toBe('pt-BR');
     expect(CHINESE_SIMPLIFIED).toBe('zh-Hans');
-    expect(PSEUDO_LOCALE).toBe('pseudo-LOCALE');
+    expect(PSEUDO_LOCALE).toBe('pseudo');
     expect(DEFAULT_LANGUAGE).toBe(ENGLISH_US);
   });
 
diff --git a/public/app/core/internationalization/constants.ts b/public/app/core/internationalization/constants.ts
index f4ab99631cc..b28e5499d92 100644
--- a/public/app/core/internationalization/constants.ts
+++ b/public/app/core/internationalization/constants.ts
@@ -7,7 +7,7 @@ export const SPANISH_SPAIN = 'es-ES';
 export const GERMAN_GERMANY = 'de-DE';
 export const BRAZILIAN_PORTUGUESE = 'pt-BR';
 export const CHINESE_SIMPLIFIED = 'zh-Hans';
-export const PSEUDO_LOCALE = 'pseudo-LOCALE';
+export const PSEUDO_LOCALE = 'pseudo';
 
 export const DEFAULT_LANGUAGE = ENGLISH_US;