diff --git a/pkg/services/sqlstore/sqlstore.go b/pkg/services/sqlstore/sqlstore.go
index 022836826de..dead55bb102 100644
--- a/pkg/services/sqlstore/sqlstore.go
+++ b/pkg/services/sqlstore/sqlstore.go
@@ -281,6 +281,10 @@ func (ss *SQLStore) buildConnectionString() (string, error) {
 			cnnstr += fmt.Sprintf("&tx_isolation=%s", val)
 		}
 
+		if ss.Cfg.IsFeatureToggleEnabled("mysqlAnsiQuotes") {
+			cnnstr += "&sql_mode='ANSI_QUOTES'"
+		}
+
 		cnnstr += ss.buildExtraConnectionString('&')
 	case migrator.Postgres:
 		addr, err := util.SplitHostPortDefault(ss.dbCfg.Host, "127.0.0.1", "5432")
diff --git a/pkg/services/sqlstore/sqlstore_test.go b/pkg/services/sqlstore/sqlstore_test.go
index 0b04716f7a8..d17ba44c9a0 100644
--- a/pkg/services/sqlstore/sqlstore_test.go
+++ b/pkg/services/sqlstore/sqlstore_test.go
@@ -72,6 +72,12 @@ var sqlStoreTestCases = []sqlStoreTest{
 		dbURL: "://invalid.com/",
 		err:   &url.Error{Op: "parse", URL: "://invalid.com/", Err: errors.New("missing protocol scheme")},
 	},
+	{
+		name:          "Sql mode set to ANSI_QUOTES",
+		dbType:        "mysql",
+		dbHost:        "[::1]",
+		connStrValues: []string{"sql_mode='ANSI_QUOTES'"},
+	},
 }
 
 func TestIntegrationSQLConnectionString(t *testing.T) {
@@ -112,5 +118,7 @@ func makeSQLStoreTestConfig(t *testing.T, dbType, host, dbURL string) *setting.C
 	_, err = sec.NewKey("password", "pass")
 	require.NoError(t, err)
 
+	cfg.IsFeatureToggleEnabled = func(key string) bool { return true }
+
 	return cfg
 }
diff --git a/pkg/services/sqlstore/sqlutil/sqlutil.go b/pkg/services/sqlstore/sqlutil/sqlutil.go
index 79290152cd0..240aa1470f2 100644
--- a/pkg/services/sqlstore/sqlutil/sqlutil.go
+++ b/pkg/services/sqlstore/sqlutil/sqlutil.go
@@ -28,9 +28,13 @@ func MySQLTestDB() TestDB {
 	if port == "" {
 		port = "3306"
 	}
+	conn_str := fmt.Sprintf("grafana:password@tcp(%s:%s)/grafana_tests?collation=utf8mb4_unicode_ci", host, port)
+	if _, present := os.LookupEnv("MYSQL_ANSI_QUOTES"); present {
+		conn_str += "&sql_mode='ANSI_QUOTES'"
+	}
 	return TestDB{
 		DriverName: "mysql",
-		ConnStr:    fmt.Sprintf("grafana:password@tcp(%s:%s)/grafana_tests?collation=utf8mb4_unicode_ci", host, port),
+		ConnStr:    conn_str,
 	}
 }