diff --git a/src/bindings/python/CMakeLists.txt b/src/bindings/python/CMakeLists.txt
index 1f8416d4bb8..81136b1464c 100644
--- a/src/bindings/python/CMakeLists.txt
+++ b/src/bindings/python/CMakeLists.txt
@@ -16,10 +16,6 @@ endif()
 
 set(PYTHON_SOURCE_DIR ${OpenVINOPython_SOURCE_DIR}/src)
 
-# TODO: Remove this condition as 76672 will be fixed
-if(CMAKE_CROSSCOMPILING AND DEFINED ENV{OE_CMAKE_TOOLCHAIN_FILE})
-    set(DISABLE_PYBIND11 ON CACHE BOOL "Whether pybind11 can be used in python bindings")
-endif()
 
 #
 # Check python requirements