diff --git a/inference-engine/src/cldnn_engine/CMakeLists.txt b/inference-engine/src/cldnn_engine/CMakeLists.txt
index 46dfd5e9fce..48bcf666245 100644
--- a/inference-engine/src/cldnn_engine/CMakeLists.txt
+++ b/inference-engine/src/cldnn_engine/CMakeLists.txt
@@ -26,6 +26,8 @@ ie_add_plugin(NAME ${TARGET_NAME}
               SOURCES ${MAIN_SRC} ${LIBRARY_HEADERS}
               VERSION_DEFINES_FOR cldnn_engine.cpp)
 
+target_compile_options(${TARGET_NAME} PRIVATE -Os)
+
 target_link_libraries(${TARGET_NAME} PRIVATE clDNN_lib pugixml::static
                                              inference_engine
                                              inference_engine_transformations
diff --git a/inference-engine/thirdparty/clDNN/kernel_selector/CMakeLists.txt b/inference-engine/thirdparty/clDNN/kernel_selector/CMakeLists.txt
index 8afd112d9e7..a4583766216 100644
--- a/inference-engine/thirdparty/clDNN/kernel_selector/CMakeLists.txt
+++ b/inference-engine/thirdparty/clDNN/kernel_selector/CMakeLists.txt
@@ -123,6 +123,8 @@ add_library("${CLDNN_BUILD__PROJ}" STATIC
     ${__CLDNN_AllSources}
   )
 
+target_compile_options(${CLDNN_BUILD__PROJ} PRIVATE -Os)
+
 set_property(TARGET "${CLDNN_BUILD__PROJ}" PROPERTY PROJECT_LABEL "${CLDNN_BUILD__PROJ_LABEL}")
 
 if(COMMAND add_cpplint_target)
diff --git a/inference-engine/thirdparty/clDNN/runtime/CMakeLists.txt b/inference-engine/thirdparty/clDNN/runtime/CMakeLists.txt
index 3fabf155ea6..3fe06b4e656 100644
--- a/inference-engine/thirdparty/clDNN/runtime/CMakeLists.txt
+++ b/inference-engine/thirdparty/clDNN/runtime/CMakeLists.txt
@@ -46,6 +46,8 @@ add_library("${CLDNN_BUILD__PROJ}" STATIC
     ${__CLDNN_AllSources}
   )
 
+target_compile_options(${CLDNN_BUILD__PROJ} PRIVATE -Os)
+
 set_property(TARGET "${CLDNN_BUILD__PROJ}" PROPERTY PROJECT_LABEL "${CLDNN_BUILD__PROJ_LABEL}")
 
 if(COMMAND add_cpplint_target)
diff --git a/inference-engine/thirdparty/clDNN/src/CMakeLists.txt b/inference-engine/thirdparty/clDNN/src/CMakeLists.txt
index 9b19f79b814..7629850fe67 100644
--- a/inference-engine/thirdparty/clDNN/src/CMakeLists.txt
+++ b/inference-engine/thirdparty/clDNN/src/CMakeLists.txt
@@ -110,6 +110,9 @@ include_directories(
 add_library("${CLDNN_BUILD__PROJ}" STATIC
     ${__CLDNN_AllSources}
   )
+
+target_compile_options(${CLDNN_BUILD__PROJ} PRIVATE -Os)
+
 set_property(TARGET "${CLDNN_BUILD__PROJ}" PROPERTY PROJECT_LABEL "${CLDNN_BUILD__PROJ_LABEL}")
 
 target_link_libraries("${CLDNN_BUILD__PROJ}" PUBLIC