diff --git a/cmake/templates/InferenceEngineDeveloperPackageConfig.cmake.in b/cmake/templates/InferenceEngineDeveloperPackageConfig.cmake.in
index 56a610cc39e..eefb5a4e132 100644
--- a/cmake/templates/InferenceEngineDeveloperPackageConfig.cmake.in
+++ b/cmake/templates/InferenceEngineDeveloperPackageConfig.cmake.in
@@ -151,8 +151,11 @@ endif()
 unset(_IE_nlohmann_json_FOUND)
 
 # inherit OpenCV from main IE project if enabled
-if ("@OpenCV_FOUND@")
-    load_cache("${cache_path}" READ_WITH_PREFIX "" OpenCV_DIR)
+if("@OpenCV_FOUND@")
+    # Use OpenCV_DIR from cache only if user doesn't define OpenCV_DIR
+    if(NOT OpenCV_DIR)
+        load_cache("${cache_path}" READ_WITH_PREFIX "" OpenCV_DIR)
+    endif()
     find_dependency(OpenCV)
 endif()
 
diff --git a/cmake/templates/OpenVINODeveloperPackageConfig.cmake.in b/cmake/templates/OpenVINODeveloperPackageConfig.cmake.in
index c6decaf418e..ab9ff478b10 100644
--- a/cmake/templates/OpenVINODeveloperPackageConfig.cmake.in
+++ b/cmake/templates/OpenVINODeveloperPackageConfig.cmake.in
@@ -71,8 +71,11 @@ foreach(component @openvino_export_components@)
 endforeach()
 
 # inherit OpenCV from main OpenVINO project if enabled
-if ("@OpenCV_FOUND@")
-    load_cache("${cache_path}" READ_WITH_PREFIX "" OpenCV_DIR)
+if("@OpenCV_FOUND@")
+    # Use OpenCV_DIR from cache only if user doesn't define OpenCV_DIR
+    if(NOT OpenCV_DIR)
+        load_cache("${cache_path}" READ_WITH_PREFIX "" OpenCV_DIR)
+    endif()
     find_dependency(OpenCV)
 endif()