diff --git a/runtime/bindings/python/src/openvino/opset8/__init__.py b/runtime/bindings/python/src/openvino/opset8/__init__.py
index e280228ae99..80711acc2f5 100644
--- a/runtime/bindings/python/src/openvino/opset8/__init__.py
+++ b/runtime/bindings/python/src/openvino/opset8/__init__.py
@@ -140,6 +140,7 @@ from openvino.opset1.ops import sigmoid
 from openvino.opset1.ops import sign
 from openvino.opset1.ops import sin
 from openvino.opset1.ops import sinh
+from openvino.opset8.ops import slice
 from openvino.opset1.ops import softmax
 from openvino.opset4.ops import softplus
 from openvino.opset2.ops import space_to_batch
diff --git a/runtime/bindings/python/src/openvino/opset8/ops.py b/runtime/bindings/python/src/openvino/opset8/ops.py
index eff68108ea7..c4a30fce7cf 100644
--- a/runtime/bindings/python/src/openvino/opset8/ops.py
+++ b/runtime/bindings/python/src/openvino/opset8/ops.py
@@ -367,3 +367,27 @@ def random_uniform(
         "op_seed": op_seed,
     }
     return _get_node_factory_opset8().create("RandomUniform", inputs, attributes)
+
+
+@nameable_op
+def slice(
+        data: NodeInput,
+        start: NodeInput,
+        stop: NodeInput,
+        step: NodeInput,
+        axes: NodeInput = None
+) -> Node:
+    """Return a node which generates Slice operation.
+
+    @param  data: The node providing input data.
+    @param  start: The node providing start indices (inclusively).
+    @param  stop: The node providing stop indices (exclusively).
+    @param  step: The node providing step values.
+    @param  axes: The optional node providing axes to slice, default [0, 1, ..., len(start)-1].
+    """
+    if axes is None:
+        inputs = as_nodes(data, start, stop, step)
+    else:
+        inputs = as_nodes(data, start, stop, step, axes)
+
+    return _get_node_factory_opset8().create("Slice", inputs)
diff --git a/runtime/bindings/python/tests/test_ngraph/test_create_op.py b/runtime/bindings/python/tests/test_ngraph/test_create_op.py
index 4672341b360..0e097122b4c 100644
--- a/runtime/bindings/python/tests/test_ngraph/test_create_op.py
+++ b/runtime/bindings/python/tests/test_ngraph/test_create_op.py
@@ -1923,3 +1923,31 @@ def test_matrix_nms():
     assert nms_node.get_output_element_type(0) == Type.f32
     assert nms_node.get_output_element_type(1) == Type.i32
     assert nms_node.get_output_element_type(2) == Type.i32
+
+
+def test_slice():
+    data_shape = [10, 7, 2, 13]
+    data = ov.parameter(data_shape, name="input", dtype=np.float32)
+
+    start = ov.constant(np.array([2, 0, 0], dtype=np.int32))
+    stop = ov.constant(np.array([9, 7, 2], dtype=np.int32))
+    step = ov.constant(np.array([2, 1, 1], dtype=np.int32))
+
+    node_default_axes = ov.slice(data, start, stop, step)
+
+    assert node_default_axes.get_type_name() == "Slice"
+    assert node_default_axes.get_output_size() == 1
+    assert node_default_axes.get_output_element_type(0) == Type.f32
+    assert tuple(node_default_axes.get_output_shape(0)) == np.zeros(data_shape)[2:9:2, ::, 0:2:1].shape
+
+    start = ov.constant(np.array([0, 2], dtype=np.int32))
+    stop = ov.constant(np.array([2, 9], dtype=np.int32))
+    step = ov.constant(np.array([1, 2], dtype=np.int32))
+    axes = ov.constant(np.array([-2, 0], dtype=np.int32))
+
+    node = ov.slice(data, start, stop, step, axes)
+
+    assert node.get_type_name() == "Slice"
+    assert node.get_output_size() == 1
+    assert node.get_output_element_type(0) == Type.f32
+    assert tuple(node.get_output_shape(0)) == np.zeros(data_shape)[2:9:2, ::, 0:2:1].shape