diff --git a/CHANGES b/CHANGES
index f65b0b07a..cc4455050 100644
--- a/CHANGES
+++ b/CHANGES
@@ -16,6 +16,8 @@ Features added
 Bugs fixed
 ----------
 
+* #10456: filter_meta_fields fails to remove more than one meta-field
+
 Testing
 --------
 
diff --git a/sphinx/domains/python.py b/sphinx/domains/python.py
index 8fc185325..a634a51d2 100644
--- a/sphinx/domains/python.py
+++ b/sphinx/domains/python.py
@@ -1068,11 +1068,11 @@ def filter_meta_fields(app: Sphinx, domain: str, objtype: str, content: Element)
     for node in content:
         if isinstance(node, nodes.field_list):
             fields = cast(List[nodes.field], node)
-            for field in fields:
+            # removing list items while iterating the list needs reversed()
+            for field in reversed(fields):
                 field_name = cast(nodes.field_body, field[0]).astext().strip()
                 if field_name == 'meta' or field_name.startswith('meta '):
                     node.remove(field)
-                    break
 
 
 class PythonModuleIndex(Index):
diff --git a/tests/test_domain_py.py b/tests/test_domain_py.py
index 61f595c23..014067e84 100644
--- a/tests/test_domain_py.py
+++ b/tests/test_domain_py.py
@@ -999,7 +999,9 @@ def test_info_field_list(app):
     text = (".. py:module:: example\n"
             ".. py:class:: Class\n"
             "\n"
+            "   :meta blah: this meta-field must not show up in the toc-tree\n"
             "   :param str name: blah blah\n"
+            "   :meta another meta field:\n"
             "   :param age: blah blah\n"
             "   :type age: int\n"
             "   :param items: blah blah\n"