diff --git a/tests/nssmock.c b/tests/nssmock.c
index 3493119f3b..d47fe7b10f 100644
--- a/tests/nssmock.c
+++ b/tests/nssmock.c
@@ -46,7 +46,11 @@ init_syms(void)
     if (real_open)
         return;
 
+# if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+# else
     VIR_MOCK_REAL_INIT(open);
+# endif
 # if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 # endif
diff --git a/tests/qemusecuritymock.c b/tests/qemusecuritymock.c
index 2dfd6c33a0..d5c711b5d7 100644
--- a/tests/qemusecuritymock.c
+++ b/tests/qemusecuritymock.c
@@ -115,7 +115,11 @@ init_syms(void)
         return;
 
     VIR_MOCK_REAL_INIT(chown);
+#if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+#else
     VIR_MOCK_REAL_INIT(open);
+#endif
 #if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 #endif
diff --git a/tests/vircgroupmock.c b/tests/vircgroupmock.c
index d922f30f34..a5c18bd7b0 100644
--- a/tests/vircgroupmock.c
+++ b/tests/vircgroupmock.c
@@ -304,7 +304,11 @@ static void init_syms(void)
     VIR_MOCK_REAL_INIT(fopen);
     VIR_MOCK_REAL_INIT(access);
     VIR_MOCK_REAL_INIT(mkdir);
+# if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+# else
     VIR_MOCK_REAL_INIT(open);
+# endif
 # if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 # endif
diff --git a/tests/virfilewrapper.c b/tests/virfilewrapper.c
index 908f7142c2..3bccca9c11 100644
--- a/tests/virfilewrapper.c
+++ b/tests/virfilewrapper.c
@@ -56,7 +56,11 @@ static void init_syms(void)
     VIR_MOCK_REAL_INIT(fopen);
     VIR_MOCK_REAL_INIT(access);
     VIR_MOCK_REAL_INIT(mkdir);
+# if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+# else
     VIR_MOCK_REAL_INIT(open);
+# endif
 # if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 # endif
diff --git a/tests/virpcimock.c b/tests/virpcimock.c
index 4eff6d70e3..ca345f37a3 100644
--- a/tests/virpcimock.c
+++ b/tests/virpcimock.c
@@ -945,7 +945,11 @@ init_syms(void)
         return;
 
     VIR_MOCK_REAL_INIT(access);
+# if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+# else
     VIR_MOCK_REAL_INIT(open);
+# endif
 # if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 # endif /* WITH___OPEN_2 */
diff --git a/tests/virtestmock.c b/tests/virtestmock.c
index 5b25b380e5..a5c3b29f39 100644
--- a/tests/virtestmock.c
+++ b/tests/virtestmock.c
@@ -46,7 +46,11 @@ static void init_syms(void)
     if (real_open)
         return;
 
+#if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+#else
     VIR_MOCK_REAL_INIT(open);
+#endif
 #if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 #endif
diff --git a/tests/virusbmock.c b/tests/virusbmock.c
index e148296b7c..c23bed4528 100644
--- a/tests/virusbmock.c
+++ b/tests/virusbmock.c
@@ -40,7 +40,11 @@ static void init_syms(void)
     if (real_open)
         return;
 
+#if defined(__GLIBC__) && defined(_FILE_OFFSET_BITS) && _FILE_OFFSET_BITS == 64
+    VIR_MOCK_REAL_INIT_ALIASED(open, "open64");
+#else
     VIR_MOCK_REAL_INIT(open);
+#endif
 #if WITH___OPEN_2
     VIR_MOCK_REAL_INIT(__open_2);
 #endif