diff --git a/@xen-orchestra/backups/Backup.js b/@xen-orchestra/backups/Backup.js
index 938aabc62..74f9af520 100644
--- a/@xen-orchestra/backups/Backup.js
+++ b/@xen-orchestra/backups/Backup.js
@@ -197,9 +197,43 @@ exports.Backup = class Backup {
     }
 
     await using(
-      Disposable.all(extractIdsFromSimplePattern(job.srs).map(_ => this._getRecord('SR', _))),
-      Disposable.all(extractIdsFromSimplePattern(job.remotes).map(id => this._getAdapter(id))),
+      Disposable.all(
+        extractIdsFromSimplePattern(job.srs).map(id =>
+          this._getRecord('SR', id).catch(error => {
+            runTask(
+              {
+                name: 'get SR record',
+                data: { type: 'SR', id },
+              },
+              () => Promise.reject(error)
+            )
+          })
+        )
+      ),
+      Disposable.all(
+        extractIdsFromSimplePattern(job.remotes).map(id =>
+          this._getAdapter(id).catch(error => {
+            runTask(
+              {
+                name: 'get remote adapter',
+                data: { type: 'remote', id },
+              },
+              () => Promise.reject(error)
+            )
+          })
+        )
+      ),
       async (srs, remoteAdapters) => {
+        // remove adapters that failed (already handled)
+        remoteAdapters = remoteAdapters.filter(_ => _ !== undefined)
+
+        // remove srs that failed (already handled)
+        srs = srs.filter(_ => _ !== undefined)
+
+        if (remoteAdapters.length === 0 && srs.length === 0) {
+          return
+        }
+
         const vmIds = extractIdsFromSimplePattern(job.vms)
 
         Task.info('vms', { vms: vmIds })
diff --git a/CHANGELOG.unreleased.md b/CHANGELOG.unreleased.md
index c158835de..2db4c2e41 100644
--- a/CHANGELOG.unreleased.md
+++ b/CHANGELOG.unreleased.md
@@ -17,6 +17,7 @@
 - [Editable number] When you are trying to edit a number and it's failing, display an error (PR [#5634](https://github.com/vatesfr/xen-orchestra/pull/5634))
 - [VM/Network] Fix `an error has occurred` when trying to sort the table by the network's name (PR [#5639](https://github.com/vatesfr/xen-orchestra/pull/5639))
 - [Backup] Try harder to avoid orphan VDI snapshots, especially with iSCSI SRs [#4926](https://github.com/vatesfr/xen-orchestra/issues/4926)
+- [Backup] Disabled or unavailable remotes and SRs don't prevent job from running [#5353](https://github.com/vatesfr/xen-orchestra/issues/5353) (PR [#5651](https://github.com/vatesfr/xen-orchestra/pull/5651))
 
 ### Packages to release